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Article ID	#26530
Title	Are chronic inflammation and its metabolic counterpart, insulin resistance, the common denominators for all chronic behavior and neurodegenerative disorders? A review of the evidence - Part VII. Depression - Its connection with chronic inflammation, Vitamin B6 depletion, disturbances in kynurenine metabolism and diabetes
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Journal	Nutr Perspect. 2020 Jan;43(1):24-26, 28-31
Author(s)	Moss J
Peer Review	No
Publication Type	Article
Abstract/Notes	In part VI of this series I ended with a discussion of the hypothesis by Oxenkrug that, when chronic inflammation combines with vitamin B6 deficiency, disturbances in kynurenine metabolism can ensure which can not only contribute to depression but type 2 diabetes. Does the author provide any clinical research to back up this hypothesis? This evidence is provided in the paper "Increased plasma levels of xanthurenic and kynurenic acids in type 2 diabetes" by Oxenkrug. This abstract is reproduced with the permission of the publisher. Full text is available by subscription.
Subject(s)	Depression Diabetes Mellitus, Type 2 Inflammation Insulin Resistance Kynurenine Neurodegenerative Diseases Vitamin B 6 Deficiency

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