• McCoy M
• Kent C
• Senzon S
• Ebrall P

• Affiliation / Foundation for Vertebral Subluxation
• Affiliation / Southern Cross University. Health and Wellbeing Research Group
• COVID-19
• Immune System
• Immunity
• Manipulation, Chiropractic / standards
• Subluxation
• World Federation of Chiropractic (WFC)

The objective of this paper is to provide a critical evaluation of the World Federation of Chiropractic’s (WFC) “Rapid Review” of the role of chiropractic in immunity and their conclusions. The WFC claims to have reviewed 7 items including an unpublished report with no citation, four studies involving enhancement of immune markers following chiropractic intervention (including enhanced respiratory burst, increased interleukin 2, and increased CD4 cell counts), a review of literature on the evidence supporting stimulation of the neuroimmunoendocrine system and a review of one hundred thousand cases of influenza managed by osteopathy during the 1918 flu pandemic.

All of the reports they reviewed demonstrated positive findings in support of manual methods such as chiropractic adjustments and manipulation in effecting a positive immune response.

Despite these positive findings, the WFC Research Committee came to the opposite conclusion that no credible, scientific evidence exists that spinal adjustment / manipulation has any clinically relevant effect on the immune system.

Our critical evaluation reveals that their conclusion is based on flawed methodology, a grossly incomplete review of the literature, unfounded interpretations of the results of the studies, and bias demonstrated by the authors. It is well established that the nervous system controls and coordinates all functions and systems of the human body including immunity and the immune system. Many in chiropractic consider that this relationship confers salutogenic benefits in people undergoing chiropractic care. The scientific literature reviewed here, while limited, demonstrates a positive, salutogenic effect from chiropractic on the human immune system. 

Author keywords: World Federation of Chiropractic, immunity, chiropractic, adjustment, manipulation, vertebral subluxation, coronavirus, COVID-19

Author affiliations: MM: Vice President, Foundation for Vertebral Subluxation; CK: President, Foundation for Vertebral Subluxation; SS: Research Fellow, Foundation for Vertebral Subluxation; PE: Health and Wellbeing Research Group, Southern Cross University

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