| Abstract/Notes |
Objective: The vertebral subluxation complex (VSC) is a foundational chiropractic concept describing biomechanical dysfunction with neurological consequences. Despite clinical relevance, its mechanisms remain poorly defined at the cellular and subcellular levels. This paper proposes an interdisciplinary framework integrating mechanobiology, cytoskeletal dynamics, and quantum biology to reinterpret VSC as a primary lesion that disrupts neuronal transmission by altering mechanotransduction and potentially decohering quantum processes in microtubules.
Discussion: A narrative synthesis was conducted, drawing on peer-reviewed evidence in mechanobiology, extracellular matrix (ECM) remodeling, microtubule function, and Orchestrated Objective Reduction (Orch-OR) theory. Key concepts include ECM stiffening, integrin-mediated signaling, microtubule stability, and quantum coherence in neural tissues. Mechanical stress from vertebral misalignment stiffens the ECM, disrupting microtubule dynamics and ion channel function via integrin-FAK-RhoA pathways. This alters synaptic plasticity, induces neuroinflammation, and may prematurely collapse quantum superpositions in neuronal microtubules- impairing consciousness, proprioception, and autonomic regulation. Chiropractic adjustments may restore alignment, normalize mechanotransduction, and reinstate quantum coherence, explaining observed neuroplastic and clinical outcomes.
Conclusion: The VSC represents a multiscale lesion—from classical biomechanics to quantum information processing. Integrating mechanobiology with Orch-OR theory offers a testable model linking spinal manipulation to cellular repair and consciousness. Future research should employ advanced neuroimaging, cellular force mapping, and quantum coherence assays to validate this framework and guide evidence-based chiropractic practice.
Author keywords: Chiropractic; Subluxation; Mechanobiology
This abstract is reproduced with the permission of the publisher. Click on the above link for free full text.
|
