• Kordonowy RA
• Norkus ST

• Adult
• Amine Oxidase (Copper-Containing)
• Dietary Supplements
• Female
• Histamine / metabolism
• Nutrition Therapy

Abstract: This is the account of a 24-year-old Caucasian female diagnosed with histamine intolerance by a chiropractic physician. This case should be of interest as it is not a condition which is routinely considered. Following years of a variety of seemingly diverse symptomatology, including suspected cerebrovascular accidents which were unable to be confirmed medically, objective data in the form of an advanced intestinal barrier assessment and a dietary antigen test were obtained. These tests provided objective verification that the patient had both elevated serum histamine and low diamine oxidase (DAO), both signs of an issue with histamine metabolism. The patient was placed on a low histamine diet, as well as supplemental diamine oxidase, and Histoplex®. After several months of following the recommended treatment, the patient experienced a reduction in her symptoms. Histamine intolerance has the potential to be causative of a wide range of symptoms, and as this case demonstrates can be overlooked by physicians of all disciplines. Consideration of histamine intolerance may need to be added to the list of differential diagnoses in patients that are not responding to other recommended treatments.

Author keywords: Histamine Intolerance, Diamine Oxidase, Low Histamine Diet, Nutritional Supplementation

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